dig in straight (balanced) lines and get that cbomb tech early.
i aimed at reactors then cbombs/shields then beacons, grabbing the other stuff on the way. only went for reactor, energy store/speed and reduce unit cost techs to start and only built reactors and cbombs. (except for the drone room, i built 8 blasters to be sure)
the chambers can cancel each other out as you dig down.
then cbombs and shields does the trick
hope that helps